Highlight

A paper from the Bellaïche lab provides novel insights into the mechanical control of morphogenesis and a paper from the Heard lab reveals how a novel level of chromosome organisation is reflected in gene regulation at the X-inactivation center.
Elphege-Pierre NoraElphege-Pierre Nora

Edith Heard's team in collaboration with Job Dekker (USA) has provided a glimpse of the regulatory landscape of the X-inactivation center and discovered a new rule for chromosome organisation in mammals in a recent publication in Nature.

Spatial partitioning of the regulatory landscape of the X-inactivation centre. Nora EP, Lajoie BR, Schulz EG, Giorgetti L, Okamoto I, Servant N, Piolot T, van Berkum NL, Meisig J, Sedat J, Gribnau J, Barillot E, Blüthgen N, Dekker J, Heard E.
Nature. 2012 Apr 11. doi : 10.1038/nature11049

 

Read the article.


Read the press release.

 

Yohanns BellaïcheYohanns Bellaïche

In a recent publication of Science, Yohanns Bellaïche's team has uncovered how global gene expression pattern leads to local regulation of cell mechanics to generate large scale tissue deformation during the control of tissue morphogenesis.

Mechanical control of morphogenesis by fat/dachsous/four-jointed planar cell polarity pathway. Bosveld F, Bonnet I, Guiaro B, Tlili S, Wang Z, Ptitalot A, Marchand R, Bardet PL, Marcq P, Graner F, Bellaïche Y.
Science. 2012 Apr 12. doi : 10.1126/science.1221071


Read the article.

Read more

Publication(s)

View all publication

Seminars, trainings

View all seminar